Croconaine rotaxane for acid activated photothermal heating and ratiometric photoacoustic imaging of acidic pH.

نویسندگان

  • Samit Guha
  • Gillian Karen Shaw
  • Trevor M Mitcham
  • Richard R Bouchard
  • Bradley D Smith
چکیده

Absorption of 808 nm laser light by liposomes containing a pH sensitive, near-infrared croconaine rotaxane dye increases dramatically in weak acid. A stealth liposome composition permits acid activated, photothermal heating and also acts as an effective nanoparticle probe for ratiometric photoacoustic imaging of acidic pH in deep sample locations, including a living mouse.

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عنوان ژورنال:
  • Chemical communications

دوره 52 1  شماره 

صفحات  -

تاریخ انتشار 2016